Monday, September 6, 2010
New drugs against cancer stem cells
Against breast and lung cancer clinical trials and new drug sustained, even in brain tumors was reported to be effective.
U.S. officials, scientists at the University of Texas, named Imetelstat substance not only to tumors, cancer stem cells, as also pointed out that attack, the experiments on mice that were exposed said.
Scientists, cancer stem cells believed to have been responsible for the proliferation of cancer, pointing to the success of this promising substance Imetelstat reason, he said.
new drugs against cancer stem cells trans
Jerry Shay and his team from the University of Texas, the new materials through the blood-brain barrier, also to indicate that a malignant brain tumor, so the substance may also be used as gliyoblastom said. Gliyoblastomun treatment more common in adults, because drugs can not cross the blood-brain barrier is very limited.
Jerry Shay and his team of clinical trials against breast and lung cancer cells sustained tried gliyoblastom Imetelstat item. Scientists investigate the effect of matter, especially in cancer stem cells has. Cancer stem cells, cancer treatments such as chemotherapy and radiotherapy resistance is often expressed against the scientists, the cancer cells in experiments Imetelstat article, as well as cancer stem cells was observed to be effective. Scientists, this effect has stopped cell division and thus allow the cancer cells to die, he said.
ARTICLE passed the blood-brain barrierCancer stem cells injected into mice for experiments after treatment was started Imetelstat. Shay and his team, during the treatment of substances through the blood-brain barrier into the saw. Scientists, Imetelstat article gives very positive results with chemotherapy and radiotherapy reported.
Shay, "the majority of cancers of the drug to attack a mechanism which can be very helpful," he said. Scientists, in another experiment Imetelstat article is also effective in prostate cancer stem cells revealed.
Research, published in the journal Clinical Cancer Research.
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